ICU-ROX: Does Conservative Oxygen Therapy in the ICU Increase Ventilator Free Days

Study Design Summary: Randomized trial of 1,000 patients of patients with less than 2 hours of invasive or noninvasive mechanical ventilation. Separated into 2 groups of conservative vs usual oxygen therapy groups. Primary outcome was ventilator free days, secondary outcomes included death at 90 and 180 days as well as others. Notes: There were manyContinue reading “ICU-ROX: Does Conservative Oxygen Therapy in the ICU Increase Ventilator Free Days”

PROSEVA: Does Prone Positioning Improve Survival in ARDS

Study Design Summary: 466 patients with severe ARDS were split roughly 50/50 into prone versus stand care groups. Prone group spent at least 16 consecutive hours per day in the prone position. To be included patients needed to be intubated and mechanically vented for ARDS for less than 36 hours. Primary end point was 28Continue reading “PROSEVA: Does Prone Positioning Improve Survival in ARDS”